Human placental lactogen (hPL) deficiency in a normal pregnancy.
نویسندگان
چکیده
A case of human placental lactogen (hPL) deficiency together with normal oestriol levels associated with a normal pregnancy in a woman in her second pregnancy is reported. The woman gave birth to a healthy male infant. The placenta was normal. Extremely low hPL levels may be compatible with the delivery of a healthy infant.
منابع مشابه
Serum human placental lactogen (HPL) levels in normal pregnancy.
It is now well established that human placenta secretes a protein hormone Human Placental Lactogen (HPL), also referred to as placental Somatomarnmotropin. It shows immunological crossreactivity with pituitary growth hormone and possesses both mammotropi.c and somatotropic effects (Jasiomovich and Maclaren, 1962, Kaplan and Grumbach 1968). This hormone is produced by syncytiotrophoblast layer o...
متن کاملIn vitro biosynthesis of human placental lactogen (HPL) by chorionic tissue and the diagnostic value of HPL in trophoblastic disease.
With an aim to elucidate the significance of Human Placental Lactogen (HPL) during gestation, I assayed the HPL and HCG concentration in the chorionic tissue and the blood. The results as follows: 1) There was a definite correlation between the HPL concentration in the maternal serum at term and the weight of the neonates, which might lead to an idea that HPL took part in the growth of fetuses ...
متن کاملProperties of biologically active messenger RNA from human placenta. Cell-free synthesis of two immunoreactive forms of placental lactogen.
In order to understand better the regulation of human placental proteins the activity of placental lactogen messenger RNA has been examined. Total RNA was extracted from normal term placentas and purified by chromatography on oligo(dT)-cellulose. The poly(A)-containing fraction stimulated amino acid incorporation 5- to 10-fold in wheat germ cell-free extracts, and immunoprecipitation of the tra...
متن کاملPre-b-HDL stimulates placental lactogen release from human trophoblast cells
Handwerger, Stuart, Geeta Datta, Brian Richardson, Carrie M. Schmidt, Tariq Siddiqi, Lisa Turzai, and G. M. Anantharamaiah. Pre-b-HDL stimulates placental lactogen release from human trophoblast cells. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E384–E389, 1999.—To examine whether pre-b-high-density lipoprotein (HDL) may be involved in regulation of human placental lactogen (hPL) release, pre-...
متن کاملHuman placental lactogen: studies of its acute metabolic effects and disposition in normal man.
The acute metabolic effects and disposition of human placental lactogen (HPL) have been studied in 15 men and 8 women during continuous intravenous infusions. The mean plasma half-life, metabolic pool size, and turnover rate of HPL are comparable to the values previously reported for human growth hormone (HGH). From the data presented, we calculate that the placenta secretes approximately 290 m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Postgraduate medical journal
دوره 60 708 شماره
صفحات -
تاریخ انتشار 1984